But Nicole Kidman, 43, and Jennifer Aniston, 41, have somehow managed to keep their twenty- something complexions while ditching the heavy eyebrows and frizzy hair of their youth.
The actresses appeared together at the premiere of their romantic comedy Just Go With It in New York looking glossy and glamorous. And it seems that working together has made them the firmest of friends.
Scroll down to see the trailer for the film...
Not a line between them: Jennifer Aniston (left) has perfected her beach babe look at 41, while Nicole Kidman is a flawless English Rose at 43
The way they were: Jennifer Aniston was a brunette in 1992 before she found fame in Friends while Nicole Kidman favoured curls in 1991
Miss Kidman replied: ‘Excuse me, you wear a bikini in the film and you look like you’re 20 years old.’
Miss Aniston, who is divorced from Brad Pitt, said she had been single for 18 months and was ‘very happy’. Miss Kidman has two children with husband Keith Urban and two adopted children with ex-husband Tom Cruise.
Model in the middle: The actresses cuddle up to co-star Brooklyn Decker in Dolce & Gabbana at the New York premiere of Just Go With It
And both ladies looked effortlessly glamorous at the screening of the film. Jennifer slipped into a strapless, floor-length black gown by Dolce & Gabbana which was split to the thigh and offered a tantalising glimpse of her toned legs.
Nicole, meanwhile, who was accompanied by Urban, went for a double leather look in a skirt and blazer by her favourite designer L'Wrenn Scott.
The 43-year-old added a demure blush-coloured shirt beneath and a pair of strappy black heels.
Classic black: Both opted for understated and elegant outfits, in contrast to their Hawaiian-themed screening
Both actresses went for understated, elegant looks while their younger co-star Brooklyn Decker celebrated her film debut with an eye-catching leopard-print dress.
The swimsuit model poured her curves into the sexy Dolce & Gabanna frock, which she teamed with purple heels.
Jennifer recently interviewed Nicole for Harper's Bazaar magazine, where the women gushed over each other's figures.
The Friends star recalls their first meeting - at the 2005 Golden Globes - where she was 'starstruck'.
Since bonding during filming of the comedy in Maui, Aniston says of her co-star: 'Now not only do I have a dear friend, I can't see myself dancing the hula with any other gal,' before describing Nicole's body as being 'a masterpiece'.
Nicole retorts: 'Excuse me, you wear a bikini in the film and you look like you're 20 years old.'
'I think that's Vaseline on the lens,' Jennifer says.
'You are a freak of nature,' Nicole says. 'You have the best body I've ever seen. And I'm a heterosexual girl. You look good morning, noon, and night.'
In an interview with Access Hollywood earlier this month, Adam Sandler also complimented his co-stars' bikini bodies.
He said of Jennifer's: 'It’s a beautiful, beautiful thing. Jennifer works hard, she eats right, you know, she does.
'She never snacks on the stuff I snack on,' Sandler said.
The swimsuit model poured her curves into the sexy Dolce & Gabanna frock, which she teamed with purple heels.
Jennifer recently interviewed Nicole for Harper's Bazaar magazine, where the women gushed over each other's figures.
The Friends star recalls their first meeting - at the 2005 Golden Globes - where she was 'starstruck'.
Walking on the wild side: Brooklyn Decker looked hot to trot in an animal print dress, teamed with purple heels, as she attended the premiere of her first movie
Nicole retorts: 'Excuse me, you wear a bikini in the film and you look like you're 20 years old.'
'I think that's Vaseline on the lens,' Jennifer says.
'You are a freak of nature,' Nicole says. 'You have the best body I've ever seen. And I'm a heterosexual girl. You look good morning, noon, and night.'
In an interview with Access Hollywood earlier this month, Adam Sandler also complimented his co-stars' bikini bodies.
He said of Jennifer's: 'It’s a beautiful, beautiful thing. Jennifer works hard, she eats right, you know, she does.
'She never snacks on the stuff I snack on,' Sandler said.
Say cheese: Jennifer poses with her co-star Adam Sandler who plays plastic surgeon Danny and pretends to be married to attract women in the movie. Also here child actors Bailee Madison, left, and Griffin Gluck
And Jennifer admitted that despite filming alongside former swimsuit model Decker, she still felt confident on set.
'I just was [feeling] pretty confident and I keep in good shape and you know, I felt pretty all right with everything.'
Adam also had good things to say about Nicole's figure: 'She’s in ridiculous shape too.'
Jennifer added: 'Have you ever seen a six-pack like that?” I actually had to touch it.'
'I just was [feeling] pretty confident and I keep in good shape and you know, I felt pretty all right with everything.'
Adam also had good things to say about Nicole's figure: 'She’s in ridiculous shape too.'
Jennifer added: 'Have you ever seen a six-pack like that?” I actually had to touch it.'
Be my date: Nicole was joined by her husband Keith Urban and the pair put on an affectionate display as they posed for photographers
Rom com: Brooklyn in a scene from the movie, setting temperatures rising in a yellow bikini
Just Go With It, which is due out on February 11, stars Adam Sandler as plastic surgeon Danny, who pretends to be married to attract women.
When he meets the woman of his dreams, played by Brooklyn, he has to rope in his office manager Katherine, played by Jennifer, and her children to complete the pretence.
Kidman puts in an eye-catching supporting role as the extremely competitive arch-nemesis.
The movie, which was filmed in Hawaii last year, is Sports Illustrated model Decker's first feature film.
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Nice to meet you: But Sandler said Aniston's body was equally admired on set during filming